apalutamide will lessen the level or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with prescription drugs which might be CYP3A4 substrates may lead to reduce publicity to these drugs.Belzutifan can be a CYP2C19 substrat

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